Publications

ACKNOWLEDGEMENTS

The Inveon small animal PET / CT scanner was funded by the NIH Shared Instrumentation grant 1S10RR031792‐01.  Acknowledgement of this grant in publications that involved the use of the small animal PET / CT system is highly appreciated.

PUBLICATIONS

Chelales E, Morhard R, Nief C, Crouch B, Everitt JI, Sag AA & Ramanujam N. Radiologic‑pathologic analysis of increased ethanol localization and ablative extent achieved by ethyl cellulose. Sci Rep 2021. 11:20700. Abstract

Zhou Z, McDougald D, Meshaw R, Balyasnikova I, Zalutsky MR, Vaidyanathan G. Labeling single domain antibody fragments with ¹⁸F using a novel residualizing prosthetic agent — N-succinimidyl 3-(1-(2-(2-(2-(2-[¹⁸F]fluoroethoxy)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)-5-(guanidinomethyl)benzoate, Nucl Med Biol. 2021. 100-101:24-35. Abstract

Zhou Z, Meshaw R, Zalutsky MR, Vaidyanathan G. Site-Specific and Residualizing Linker for ¹⁸F Labeling with Enhanced Renal Clearance: Application to an Anti-HER2 Single-Domain Antibody Fragment. J Nucl Med. 2021, 62(11):1624-1630. Abstract

Zhou Z, Zalutsky MR, Vaidyanathan G. Labeling a TCO-functionalized single domain antibody fragment with ¹⁸F via inverse electron demand Diels Alder cycloaddition using a fluoronicotinyl moiety-bearing tetrazine derivative. Bioorg Med Chem. 2020, 28(17):115634. Abstract

Du K, Chitneni SK, Suzuki A, Wang Y, Henao R, Hyun J, Premont RT, Naggie S, Moylan CA, Bashir MR, Abdelmalek MF, Diehl AM.  Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression.  Cellular and Molecular Gastroenterology and Hepatology.  2020;S2352-345X.  Abstract

Liu Y, Carpenter AB, Pirozzi CJ, Yuan H, Waitkus MS, Zhou Z, Hansen L, Seywald M, Odion R, Greer PK, Hawk T, Chin BB, Vaidyanathan G, Zalutsky MR, Yan H, Vo-Dinh T.  Non-invasive sensitive brain tumor detection using dual-modality bioimaging nanoprobe.  Nanotechnology.  2019;30:275101.  Abstract

Zhou Z, McDougald DL, Devoogdt N, Zalutsky MR, Vaidyanathan G.  Labeling single domain antibody fragments with fluorine-18 using 2,3,5,6-tetrafluorophenyl 6-[¹⁸F]fluoronicotinate resulting in high tumor to kidney ratios.  Molecular Pharmaceutics.  2019;16:214-226.  Abstract

Zhou Z, Devoogdt N, Zalutsky MR, Vaidyanathan G.  An efficient method for labeling single domain antibody fragments with ¹⁸F using tetrazine-trans-cyclooctene ligation and a renal brush border enzyme-cleavable linker.  Bioconjugate Chemistry.  2018;29:4090-4103.  Abstract

Gedeon PC, Schaller TH, Chitneni SK, Choi BD, Kuan C-T, Suryadevara CM, Snyder DJ, Schmittling RJ, Szafranski SE, Cui X, Healy PN, Herndon II JE, McLendon RE, Keir ST, Archer GE, Reap EA, Sanchez-Perez L, Bigner DD, Sampson JH.  A rationally designed fully human EGFRvIII:CD3-targeted bispecific antibody redirects human T cells to treat patient-derived intracerebral malignant glioma.  Clinical Cancer Research.  2018;24:3611-3631.  Abstract

Chitneni SK, Yan H, Zalutsky MR.  Synthesis and evaluation of an ¹⁸F-labeled triazinediamine analogue for imaging mutant IDH1 expression in gliomas by PET.  ACS Medicinal Chemistry Letters.  2018;9:606-611.  Abstract

Zhou Z, Chitneni SK, Devoogdt N, Zalutsky MR, Vaidyanathan G.  Fluorine-18 labeling of an anti-HER2 VHH using a residualizing prosthetic group via a strain-promoted click reaction: chemistry and preliminary evaluation.  Bioorganic Medicinal Chemistry.  2018;26:1939-1949.  Abstract

Zhou Z, Vaidyanathan G, McDougald D, Kang CM, Balyasnikova I, Devoogdt N, Ta AN, McNaughton BR, Zalutsky MR.  Fluorine-18 labeling of the HER2-targeting single-domain antibody 2Rs15d using a residualizing label and preclinical evaluation.  Molecular Imaging and Biology.  2017;19:867-877.  Abstract

Chin BB, McDougald D, Weitzel DH, Hawk T, Reiman RE, Zalutsky MR, Vaidyanathan G.  Synthesis and preliminary evaluation of 5-[¹⁸F]fluoroleucine.  Current Radiopharmaceuticals.  2017;10:41-50.  Abstract

Vaidyanathan G, McDougald D, Choi J, Koumarianou E, Weitzel D, Osada T, Lyerly HK, Zalutsky MR.  Preclinical evaluation of ¹⁸F-labeled anti-HER2 nanobody conjugates for imaging HER2 receptor expression by immuno-PET.  Journal of Nuclear Medicine.  2016;57:967-973.  Abstract

Burt T, Rouse DC, Lee K, Wu H, Layton AT, Hawk TC, Weitzel DH, Chin BB, Cohen-Wolkowiez M, Chow SC, Noveck RJ.  Intraarterial microdosing: a novel drug development approach, proof-of-concept PET study in rats.  Journal of Nuclear Medicine.  2015; 56:1793-1799.  Abstract