Rajan T. Gupta, M.D.

  • Associate Professor of Radiology
  • Assistant Professor of Surgery
  • Director, Abdominal Imaging Fellowship Program
  • Director, Duke Radiology Continuing Medical Education
Department/Division
  • Abdominal Imaging
Address DUMC Box 3808
Durham, NC 27710
Telephone 919-684-7366
Fax 919-684-7129
Training
  • MD, Northwestern University Feinberg School of Medicine, 2003
Residency
  • Diagnostic Radiology, Advocate Illinois Masonic Medical Center, 2008
Fellowship
  • Abdominal Imaging, Duke University Medical Center, 2009
National Roles
  • Scientific Program Subcommittee, American Roentgen Ray Society
  • Gastrointestinal Radiology Subcommittee, Scientific Program Committee, Radiological Society of North America
  • Prostate Cancer Disease Focused Panel, Society of Abdominal Radiology
Clinical Interests
  • MRI of the hepatobiliary system

  • Multiparametric MRI of prostate cancer

  • Abdominal imaging with CT, MRI, and ultrasound
  • Research Interests
  • Multiparametric MR imaging of prostate cancer

  • MR imaging of the hepatobiliary system

  • Applications of dual energy CT in the abdomen and pelvis
  • Grants Clinical Principal Investigator, Duke-Coulter Translational Partnership Grant for project entitled, "Finite Element Modeling-based Acoustic Radiation Force Impulse and Magnetic Resonance Image Registration for Focal Prostate Cancer Procedures."

    Clinical Principal Investigator, Duke-Coulter Translational Partnership Grant for project entitled, “Registration of Multi-parametric MR and Quantitative Shear Wave Elasticity Images for Focal Prostate Cancer Procedures.”

    • Gupta RT, Kauffman CR, Polascik TJ, Taneja SS, Rosenkrantz AB. The state of prostate MRI in 2013. Oncology. 2013 Apr;27(4):262-70.
      Abstract
    • Gupta RT, Iseman CM, Leyendecker JR, Shyknevsky I, Merkle EM, Taouli B. Diagnosis of focal nodular hyperplasia with MRI: multicenter retrospective study comparing gadobenate dimeglumine to gadoxetate disodium. AJR Am J Roentgenol. 2012 Jul;199(1):35-43.
      Abstract
    • Bashir MR, Gupta RT, Davenport MS, Allen BC, Jaffe TA, Ho LM, Boll DT, Merkle EM. Hepatocellular carcinoma in a North American population: Does hepatobiliary MR imaging with Gd-EOB-DTPA improve sensitivity and confidence for diagnosis? J Magn Reson Imaging. 2012 Sep 25;.
      Abstract
    • Bashir MR, Gupta RT. MDCT evaluation of the pancreas: nuts and bolts. Radiol Clin North Am. 2012 May;50(3):365-77.
      Abstract
    • Ho LM, Marin D, Neville AM, Barnhart HX, Gupta RT, Paulson EK, Boll DT. Characterization of adrenal nodules with dual-energy CT: can virtual unenhanced attenuation values replace true unenhanced attenuation values? AJR Am J Roentgenol. 2012 Apr;198(4):840-5.
      Abstract
    • Gupta RT, Marin D, Boll DT, Husarik DB, Davis DE, Feuerlein S, Merkle EM. Hepatic hemangiomas: difference in enhancement pattern on 3T MR imaging with gadobenate dimeglumine versus gadoxetate disodium. Eur J Radiol. 2012 Oct;81(10):2457-62.
      Abstract
    • Bashir MR, Husarik DB, Ziemlewicz TJ, Gupta RT, Boll DT, Merkle EM. Liver MRI in the hepatocyte phase with gadolinium-EOB-DTPA: does increasing the flip angle improve conspicuity and detection rate of hypointense lesions? J Magn Reson Imaging. 2012 Mar;35(3):611-6.
      Abstract
    • Husarik DB, Gupta RT, Ringe KI, Boll DT, Merkle EM. Contrast enhanced liver MRI in patients with primary sclerosing cholangitis: inverse appearance of focal confluent fibrosis on delayed phase MR images with hepatocyte specific versus extracellular gadolinium based contrast agents. Acad Radiol. 2011 Dec;18(12):1549-54.
      Abstract
    • Lungren MP, Christensen JD, Coleman RE, Gupta RT. PET appearance of tuberculous empyema necessitans. Clin Nucl Med. 2011 Oct;36(10):939-41.
      Abstract
    • Bashir MR, Zhong X, Dale BM, Gupta RT, Boll DT, Merkle EM. Automated patient-tailored screening of the liver for diffuse steatosis and iron overload using MRI. AJR Am J Roentgenol. 2013 Sep;201(3):583-8.
      Abstract
    • Feuerlein S, Gupta RT, Boll DT, Merkle EM. Hepatocellular MR contrast agents: enhancement characteristics of liver parenchyma and portal vein after administration of gadoxetic acid in comparison to gadobenate dimeglumine. Eur J Radiol. 2012 Sep;81(9):2037-41.
      Abstract
    • Miller CM, Gupta RT, Paulson EK, Neville AM, Bashir MR, Merkle EM, Boll DT. Effect of organ enhancement and habitus on estimation of unenhanced attenuation at contrast-enhanced dual-energy MDCT: concepts for individualized and organ-specific spectral iodine subtraction strategies. AJR Am J Roentgenol. 2011 May;196(5):W558-64.
      Abstract
    • Neville AM, Gupta RT, Miller CM, Merkle EM, Paulson EK, Boll DT. Detection of renal lesion enhancement with dual-energy multidetector CT. Radiology. 2011 Apr;259(1):173-83.
      Abstract
    • Feuerlein S, Boll DT, Gupta RT, Ringe KI, Marin D, Merkle EM. Gadoxetate disodium-enhanced hepatic MRI: dose-dependent contrast dynamics of hepatic parenchyma and portal vein. AJR Am J Roentgenol. 2011 Jan;196(1):W18-24.
      Abstract
    • Gupta RT, Brady CM, Lotz J, Boll DT, Merkle EM. Dynamic MR imaging of the biliary system using hepatocyte-specific contrast agents. AJR Am J Roentgenol. 2010 Aug;195(2):405-13.
      Abstract
    • Coursey CA, Nelson RC, Boll DT, Paulson EK, Ho LM, Neville AM, Marin D, Gupta RT, Schindera ST. Dual-energy multidetector CT: how does it work, what can it tell us, and when can we use it in abdominopelvic imaging? Radiographics. 2010 Jul-Aug;30(4):1037-55.
      Abstract
    • Gupta RT, Ho LM, Marin D, Boll DT, Barnhart HX, Nelson RC. Dual-energy CT for characterization of adrenal nodules: initial experience. AJR Am J Roentgenol. 2010 Jun;194(6):1479-83.
      Abstract
    • Ringe KI, Gupta RT, Brady CM, Massey CM, Hahn A, Galanski M, Merkle EM, Lotz J. Respiratory-triggered three-dimensional T2-weighted MR cholangiography after injection of gadoxetate disodium: is it still reliable? Radiology. 2010 May;255(2):451-8.
      Abstract
    • Ringe KI, Husarik DB, Gupta RT, Boll DT, Merkle EM. Hepatobiliary transit times of gadoxetate disodium (Primovist®) for protocol optimization of comprehensive MR imaging of the biliary system--what is normal? Eur J Radiol. 2011 Aug;79(2):201-5.
      Abstract
    • Gupta RT, Kakarla RK, Kirshenbaum KJ, Tapson VF. D-dimers and efficacy of clinical risk estimation algorithms: sensitivity in evaluation of acute pulmonary embolism. AJR Am J Roentgenol. 2009 Aug;193(2):425-30.
      Abstract
    • Gupta RT, Wadhwa RP, Learch TJ, Herwick SM. Lisfranc injury: imaging findings for this important but often-missed diagnosis. Curr Probl Diagn Radiol. 2008 May-Jun;37(3):115-26.
      Abstract
    • Gupta RT, Vankoski S, Novak RA, Dias LS. Trunk kinematics and the influence on valgus knee stress in persons with high sacral level myelomeningocele. J Pediatr Orthop. 2005 Jan-Feb;25(1):89-94.
      Abstract
    • Marin D, Choudhury KR, Gupta RT, Ho LM, Allen BC, Schindera ST, Colsher JG, Samei E, Nelson RC. Clinical impact of an adaptive statistical iterative reconstruction algorithm for detection of hypervascular liver tumours using a low tube voltage, high tube current MDCT technique. Eur Radiol. 2013 Jul 6;.
      Abstract
    • Breault SR, Heye T, Bashir MR, Dale BM, Merkle EM, Reiner CS, Faridi KF, Gupta RT. Quantitative dynamic contrast-enhanced MRI of pelvic and lumbar bone marrow: effect of age and marrow fat content on pharmacokinetic parameter values. AJR Am J Roentgenol. 2013 Mar;200(3):W297-303.
      Abstract
    • Gupta RT. Evaluation of the biliary tree and gallbladder with hepatocellular MR contrast agents. Curr Probl Diagn Radiol. 2013 Mar-Apr;42(2):67-76.
      Abstract
    • Reiner CS, Merkle EM, Bashir MR, Walle NL, Nazeer HK, Gupta RT. JOURNAL CLUB: MRI Assessment of Biliary Ductal Obstruction: Is There Added Value of T1-Weighted Gadolinium-Ethoxybenzyl-Diethylenetriamine Pentaacetic Acid-Enhanced MR Cholangiography? AJR Am J Roentgenol. 2013 Jul;201(1):W49-56.
      Abstract
    • Huang SY, Kim CY, Miller MJ, Gupta RT, Lessne ML, Horvath JJ, Boll DT, Evans PD, Befera NT, Krishnan P, Chan JL, Merkle EM. Abdominopelvic and Lower Extremity Deep Venous Thrombosis: Evaluation With Contrast-Enhanced MR Venography With a Blood-Pool Agent. AJR Am J Roentgenol. 2013 Jul;201(1):208-14.
      Abstract
    • Allen BC, Bashir MR, Dale BM, Heye TJ, Gupta RT, Merkle EM. Bone marrow enhancement during time-resolved magnetic resonance angiography of the pelvis. J Comput Assist Tomogr. 2013 May-Jun;37(3):458-62.
      Abstract
    • Bashir MR, Mody R, Neville A, Javan R, Seaman D, Kim CY, Gupta RT, Jaffe TA. Retrospective assessment of the utility of an iron-based agent for contrast-enhanced magnetic resonance venography in patients with endstage renal diseases. J Magn Reson Imaging. 2013 Oct 15;.
      Abstract
    • Paxton BE, Kim CY, Miller MJ, Gupta RT. Successful Endovascular Management of a Transected Horseshoe Kidney. J Surg Rad 2011; 2(1): 80-85.
    • Langman EL, Hertzberg BS, Boyd BK, Gupta RT.  Dichorionic, diamnionic twin pregnancy discordant for anencephaly: Report of two cases and literature review.  Radiology Case Reports (Online) 2013;8:843
    • Davis DE, Lagoo AS, Gupta RT.  Nodular Regenerative Hyperplasia in the setting of Budd-Chiari Syndrome: Application of MR with Hepatobiliary Contrast Agents with Histologic Confirmation.  J Surg Rad 2012; 3(4): 224-229.