Faculty & Staff
Edward F. Patz Jr., M.D.
James and Alice Chen Distinguished Professor of Radiology
About
Department/Division
Radiology, Cardiothoracic Imaging
Current Appointments & Affiliations
James and Alice Chen Distinguished Professor of Radiology, Radiology, Cardiothoracic Imaging 2004
Professor of Radiology, Radiology, Cardiothoracic Imaging 1999
Professor in Pathology, Pathology 2001
Professor in Pharmacology & Cancer Biology, Pharmacology & Cancer Biology 2002
Member of the Duke Cancer Institute, Duke Cancer Institute 1991
Background
Education, Training, & Certifications
B.S. 1980, Duke University1980
M.D. 1985, University of Maryland School of Medicine1985
Intern in Medicine, Brigham And Women's Hospital, Brockton West Roxbury Va Medical Center1984 - 1985
Resident, Radiology, Brigham And Women's Hospital, Harvard University 1986 - 1990
Chief Resident in Radiology, Brigham And Women's Hospital, Harvard University 1988 - 1989
Thoracic ImagingFellow, Brigham And Women's Hospital, Harvard University 1989 - 1990
Duke Appointment History
Assistant Professor of Radiology1991 - 1995
Associate Professor of Radiology1995 - 1997
Associate Professor of Radiology with Tenure1997 - 1998
Interests & Expertise
Overview
There are numerous ongoing clinical studies primarily focused on the early detection of cancer.
The basic science investigations in our laboratory concentration on three fundamental translational areas,
1) Development of molecular imaging probes - We have used several different approaches to develop novel imaging probes that characterize and phenotype tumors.
2) Discovery of novel lung cancer biomarkers - We explored the use of proteomics, autoantibodies, and genomics to discover blood and tissue biomarkers for early cancer detection and phenotyping of cancer.
3) Host response to cancer - We study the native immune response to tumors as this may provide cues to relevant diagnostic and therapeutic targets. Most recently we have focused on intratumoral lymphocytes and their specific tumor antigens.