Edward F. Patz Jr., M.D.

  • James and Alice Chen Professor of Radiology
  • Professor in Pathology
  • Professor in Pharmacology & Cancer Biology
Department/Division
  • Cardiothoracic Imaging
Address DUMC Box 3808
Durham, NC 27710
Telephone 919-684-7311
Fax 919-684-7168
Training
  • MD, University of Maryland School of Medicine, 1985
Residency
  • Radiology, Brigham and Women's Hospital, 1985-1990
Fellowship
  • Thoracic Imaging, Brigham and Women's Hospital, 1989-1990
National Roles
  • Editorial Board, Cancer
  • Editorial Board, Journal of Thoracic Oncology
  • Editorial Board, Lung Cancer
Research Interests There are numerous ongoing clinical and basic science investigations in the Thoracic Radiology Section.

Our laboratory work focuses on three fundamental translational areas:

  • Development of molecular imaging probes - We have used several different approaches, including phage display, and in collaboration with our colleagues in the Chemistry Department, a mass spectrometry based method. These efforts are to develop novel imaging probes that characterize and phenotype tumors.

  • Discovery of novel lung cancer biomarkers – We have used a proteomics approach to discover serum protein biomarkers and developed a protein microarray for the detection of serum autoantibodies. These biomarkers are being evaluated as serum tests for the diagnosis of lung cancer.

  • Early cancer detection and understanding metastasis – In our effort to improve early detection strategies, we have several projects that study the process of metastasis. We are trying to understand the tumor-host interaction, and possible regulatory effects of the immune response in tumors.